High-flow nasal oxygen therapy (HFNOT) is increasingly used as part of both ward-based and critical care management of respiratory failure. Respiratory failure is distressing for patients and treatment modalities currently in use may be associated with discomfort from upper airway drying, tightly fitting facemasks, and resultant complications such as skin breakdown. Invasive ventilation is also associated with a number of complications including ventilator-associated pneumonia.
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