Quick Details
CAS No.:120011-70-3
Other Names:Donepezil HCL
MF:C24H29NO3
EINECS No.:120011-70-3
Place of Origin: China (Mainland)
Type:Agrochemical Intermediates
Purity:98.0%min, 99%
Application:Organic Synthesis, antibacterial
Appearance:White Powder
Product Name:Donepezil hydrochloride
Apperance:White to off-white powder
Donepezil is a noncompetitive acetylcholineesterase inhibitor, which can readily cross the blood brain barrier and increase the concentration of cortical acetylcholine. It is known that Donepezil is a useful tool in the study of Alzheimer's disease. Studies indicate that Donepezil protects the brain against diisopropylfluorophosphate-induced effects. Studies indicate that Donepezil selectively inhibits acetylcholineesterase, whereas it has little effect on butyrylcholinesterase. Alternate studies suggest that Donepezil increases the concentration of extracellular acetylcholine in the cerebral cortex and hippocampus of rats.